娄筱叮  

       蛋白质在活细胞内变化快，浓度差异大，导致难以精准测量，是活细胞中蛋白质检测中的科学技术难点。娄筱叮教授针对目前活细胞中蛋白质检测方法的局限性，选取抗体识别位点处的多肽序列，设计穿过细胞膜屏障的多肽序列，合成光稳定性优异的信号分子，使用多种方法共价连接功能模块，开发模块化多肽探针系统，实现了复杂活细胞环境中蛋白质的精准识别与定量、动态分析，并取得以下成果：1）调节氨基酸序列的阳离子密度和疏水性，增加穿过细胞膜屏障的能力，提高探针入胞效率；2）优化氨基酸序列的构象和空间构型，增强与靶标蛋白质的亲和力，增强识别特异性；3）合成光谱匹配，可后修饰的聚集型信号分子，调控信号输出模块设计原理，降低背景干扰，提高检测信噪比。

1. 蛋白质分析生物传感芯片，第16届华北五省市化学学术研讨会，中国山西太原，2025.07.15-07.19.

2. 蛋白分析化学方法及传感器件开发，科技女性高层次-理工前沿、人工智能、医工交叉巾帼科技创新沙龙，中国武汉，2025.06.28.

3. 蛋白质原位动态分析方法及生物传感器件研发，第31期“清涟论坛”——化学生物学前沿论坛，中国武汉，2025.06.07.

4. 蛋白质分析化学方法及传感器件开发，第九届《药学学报》药学前沿学术研讨会暨《药学学报》两刊编委会会议，中国桂林，2025.04.18-04.21.

5. 蛋白质分析化学，中国化学会第十三届全国化学生物学学术会议，中国湖南长沙，2025.04.11-04.15.

6. 轨迹与突破：一个蛋白质分析从业者的十年探索日志，2025年IUPAC全球女化学家早餐会武汉分会，中国武汉，2025.02.27.

7. Fluorescent peptide probes for living cell proteins analysis，Singapore International Chemistry Conference (SICC-12) : AIE Chemistry & Materials，Singapore，2024.12.09-12.13
   

8. 蛋白质传感技术的开发与应用，Journal of Molecular Biology (JMB)期刊分子生物学前沿论坛，线上，2024.11.06
   

9. 活细胞蛋白质分析新方法，中国化学会第十七届固态化学与无机合成学术会议，中国桂林，2024.10.11-10.13.
   

10. 蛋白质活细胞分析及生物传感器件，2024纳米材料与器件创新发展大会，中国温州，2024.09.20-09.23.
    

11. Fluorescent peptide probes for living cell proteins analysis，第十八届中国国际多肽研讨会（the 18th Chinese International Peptide Symposium (CPS)），中国香港，2024.06.30-07.02.
    

12. 中国化学会第34届学术年会，中国广州，2024.6.15-6.18.
    

13. 第四届微纳米技术与医疗健康创新大会，中国武汉，2024.5.25-5.27.
    

14. 中国化学会第八届菁青论坛，中国合肥，2024.4.5-4.7.
    

15. ACS Materials Spotlight —翔龙鸣凤科学论坛，中国深圳，2024.4.2.
    

16. 第5届荧光生物分子及其构建模块国际会议，中国香港，2024.3.10-3.13.
    

17. 第15届原子尺度表面、界面和纳米结构国际会议，中国苏州，2024.5.10-5.13.
    

18. 2024武汉分析+国际峰会，中国武汉，2024.3.22-3.24.
    

19. Angewandte Advances at Nano+论坛，Angewandte Chemie，中国苏州， 2023.11.24.
    

20. 中国感光学会光学传感与诊疗专委会成立大会暨第一届光学传感与诊疗学术研讨会，中国北京，2023.11.17-11.20.
    

21. 《聚集体》科学论坛:纳米生物分论坛(China manomedicine)，中国广州，2023.11.4-11.7.
    

22. 中国化学会第十四届全国分析化学年会，中国深圳，2023.11.2-2023.11.5.
    

23. 湖北省化学化工学会第四届应用化学年会，中国武汉，2023.10.27-2023.10.28.
    

24. IMED期刊青年论坛，线上，2023.07.27.
    

25. 中国化学会第十六届生物无机化学会议暨金属化学生物学学术会议，中国广州，2023.7.28-7.31.
    

26. 中国科协仿生新概念材料国际青年科学家沙龙，2022.11.18-19.

27. 聚集体科学前沿论坛，2022.09.14.

28. 仿生高中低温超浸润研讨会，苏州, 中国，2021.06.26-27.

29. 聚集体科学国际研讨会暨聚集诱导发光研究20周年，广州, 中国，2021.07.25-28.

30. 中国化学会第32届学术年会, 珠海, 中国，2021.04.19-22.

31. 中国化学会第一届分子聚集发光暨第二届华人聚集诱导发光学术讨论会, 上海, 中国，2021.04.09-11. 

32. The 18th Asian Chemical Congress and The 20th General Assembly of the Federation of Asian Chemical Societies, Taipei, 2019.12.08-12.

33. 第11届化学生物学会议, 广州, 中国，2019.11.19-22.

34. 第二十次全国电化学会议, 长沙，中国，2019.10.25-28.

35. 2018 International Conference on Novel Functional Materials (ICNFM2018), Anshan, China, 2018.09.16-18.

36. E-MRS 2018 Spring Meeting, Strasbourg, France, 2018.06.19-21.

37. 中国化学会第13届分析化学年会，西安，中国，2018.06.14-17.

38. 中国化学会第31届学术年会，杭州，中国，2018.05.05-08.

39. 2017年先进材料与纳米技术研讨会（武汉市科协青年科学家论坛）湖北省化学化工学会物理化学年会，武汉，中国，2017.12.14. 

40. 湖北省化学化工学会分析化学专业委员会第二十一届学术年会，武汉，中国，2017.11.18. 

41. 第一届海峡两岸生物医学前沿交叉学术研讨会，西安，中国，2017.10.13.

42. 中国化学会第十届全国化学生物学学术会议，武汉，中国，2017.09.23. 

43. Wiley专刊发布会暨AIE发展前沿学术研讨会, 北京，中国，2017.03.26 

44. 中国科学院兰州化学物理研究所“精准分离分析”系列论坛，兰州，中国，2016.12.06 

45. The 2nd International Symposium on Aggregation-Induced Emission，Guangzhou, China, 2015.05.25-18

近期汇总

1. Wu, Xia, Hu, Yuxuan, Wang, Quan, Zhang, Wei, Liu, Tao, Xia, Fan, Lou, Xiaoding(*), Pu, Kanyi. (2026). Molecular rotor-based probes for protein monitoring in biomedical research. Nature Reviews Chemistry, 10(5), 350-366.
   

   

2. Wu, Meng, Xue, Liru, Guo, Yican, Dong, Xiaoqi, Chen, Zhaojun, Wei, Simin, Yi, Xiaoqing, Li, Yinuo, Zhang, Jinjin,Zhou, Su, Wu, Mingfu, Lou, Xiaoding(*), Dai, Jun, Xia, Fan, Wang, Shixuan. (2023). Microenvironmentally Responsive Chemotherapeutic Prodrugs and CHEK2 Inhibitors Self-Assembled Micelles: Protecting Fertility and Enhancing Chemotherapy. Advanced Materials, 35(11), 2210017.

   
   

3. Jiang, Ruming, Dai, Jun, Dong, Xiaoqi, Wang, Quan, Meng, Zijuan, Guo, Jingjing, Yu, Yongjiang, Wang, Shixuan, Xia, Fan, Zhao, Zujin, Lou, Xiaoding(*), Tang, Ben Zhong. (2021). Improving Image-Guided Surgical and Immunological Tumor Treatment Efficacy by Photothermal and Photodynamic Therapies Based on a Multifunctional NIR AIEgen. Advanced Materials, 33(22), 2101158.
   

   
   

4. Jia, Hui, Ding, Defang, Hu, Jingjing, Dai, Jun, Yang, Juliang, Li, Guogang, Lou, Xiaoding(*), Xia, Fan. (2021). AIEgen-Based Lifetime-Probes for Precise Furin Quantification and Identification of Cell Subtypes. Advanced Materials, 33(45), 2104615.

   
   

5. Hu, Liming, Cao, Wenbing, Jiang, Yihaofan, Cai, Wenkang, Lou, Xiaoding(*), Liu, Tao. (2024). Designing artificial fluorescent proteins and biosensors by genetically encoding molecular rotor-based amino acids. Nature Chemistry, 16(12), 1960-1971.
   

   

6. Wang, Fengmei, Shifa, Tofik A., Yu, Peng, He, Peng, Liu, Yang, Wang, Feng, Wang, Zhenxing, Zhan, Xueying, Lou, Xiaoding(*), Xia, Fan, He, Jun. (2018). New Frontiers on van der Waals Layered Metal Phosphorous Trichalcogenides.Advanced Functional Materials, 28(37), 1802151.
   

   

7. Wu, Xia, Wu, Jun, Dai, Jun, Chen, Biao, Chen, Zhe, Wang, Shixuan, Wu, Feng, Lou, Xiaoding(*), Xia, Fan. (2021). Aggregation-induced emission luminogens reveal cell cycle-dependent telomerase activity in cancer cells.National Science Review, 8(6), nwaa306.
   

   

8. Xia, Fan, Wu, Jun, Wu, Xia, Hu, Qinyu, Dai, Jun, Lou, Xiaoding(*). (2019). Modular Design of Peptide- or DNA-Modified AIEgen Probes for Biosensing Applications. Accounts of Chemical Research, 52(11), 3064-3074.
   
   

   

9. Zheng, Zhi, Zhang, Hongyuan, Zhou, Ning, Fu, Jifa, Li, Haiyang, He, Xiaoyu, Cheng, Yong, Zhuge, Fuwei, Lou, Xiaoding(*), Zhai, Tianyou, Xia, Fan. (2026). The Precise Modulation of Probe Effective Charges by Debye Length for Enhancing Performance of Aptamer-FET Biosensors. Angewandte Chemie International Edition, 65(13), e19635.
   

   

10. Dai, Jun, Hu, Yuxin, Liu, Weiyong, Liu, Hong, Wang, Shixuan, Xia, Fan, Lou, Xiaoding(*). (2025). Cell-Sensing Analogue Nanopore for Rapid Detection of Protein-Related Targets. Angewandte Chemie International Edition, 64(11), e202421721.
    

    

11. Hu, Jing-Jing, Lin, Niya, Zhang, Yunfan, Xia, Fan, Lou, Xiaoding(*). (2024). Nanofibers in Organelles: From Structure Design to Biomedical Applications. Angewandte Chemie International Edition, 63(5), e202313139.
    

    

12. Hu, Jing-Jing, Yuan, Lizhen, Zhang, Yunfan, Kuang, Jing, Song, Wen, Lou, Xiaoding(*), Xia, Fan, Yoon, Juyoung. (2024). Photo-Controlled Calcium Overload from Endogenous Sources for Tumor Therapy. Angewandte Chemie International Edition, 63(9), e202317578.
    

    

13. Wu, Xia, Hu, Jing-Jing, Duan, Chong, Liu, Rui, Xia, Fan, Lou, Xiaoding(*). (2024). A Universal and Programmable Platform based on Fluorescent Peptide-Conjugated Probes for Detection of Proteins in Organelles of Living Cells. Angewandte Chemie International Edition, 63(17), e202400766.
    

    

14. Qiao, Yujuan, Hu, Jing-Jing, Hu, Yuxin, Duan, Chong, Jiang, Wenlian, Ma, Qun, Hong, Yuning, Huang, Wei Hua, Xia, Fan, Lou, Xiaoding(*). (2023). Detection of Unfolded Cellular Proteins Using Nanochannel Arrays with Probe-Functionalized Outer Surfaces. Angewandte Chemie International Edition, 62(43), e202309671.
    

    

15. Dai, Jun, Hu, Jing-Jing, Dong, Xiaoqi, Chen, Biao, Dong, Xiyuan, Liu, Rui, Xia, Fan, Lou, Xiaoding(*). (2022). Deep Downregulation of PD-L1 by Caged Peptide-Conjugated AIEgen/miR-140 Nanoparticles for Enhanced Immunotherapy. Angewandte Chemie International Edition, 61(18), e202117798.
    

    

16. Duan, Chong, Hu, Jing-Jing, Liu, Rui, Dai, Jun, Duan, Mojie, Yuan, Lizhen, Xia, Fan, Lou, Xiaoding(*). (2021). Spatial Order of Functional Modules Enabling Diverse Intracellular Performance of Fluorescent Probes. Angewandte Chemie International Edition, 60(33), 18280-18288.
    

    

17. Yang, Juliang, Dai, Jun, Wang, Quan, Cheng, Yong, Guo, Jingjing, Zhao, Zujin, Hong, Yuning, Lou, Xiaoding(*), Xia, Fan. (2020). Tumor-Triggered Disassembly of a Multiple-Agent-Therapy Probe for Efficient Cellular Internalization. Angewandte Chemie International Edition, 59(46), 20405-20410.
    

    

18. Cheng, Yong, Sun, Chunli, Liu, Rui, Yang, Juliang, Dai, Jun, Zhai, Tianyou, Lou, Xiaoding(*), Xia, Fan. (2019). A Multifunctional Peptide-Conjugated AIEgen for Efficient and Sequential Targeted Gene Delivery into the Nucleus. Angewandte Chemie International Edition, 58(15), 5049-5053.
    

    

19. Cheng, Yong, Dai, Jun, Sun, Chunli, Liu, Rui, Zhai, Tianyou, Lou, Xiaoding(*), Xia, Fan. (2018). An Intracellular H2O2-Responsive AIEgen for the Peroxidase-Mediated Selective Imaging and Inhibition of Inflammatory Cells. Angewandte Chemie International Edition, 57(12), 3123-3127.
    

    

20. Zhang, Wei, Chen, Ziling, Xiong, Chen, Yuan, Lizhen, Hu, Jing-Jing, Dai, Jun, Xia, Fan, Lou, Xiaoding(*). (2024). A Peptide-Copper Self-Assembled Nanoparticle for Enhanced Cuproptosis by Metabolic Reprogramming in Tumor Cells. ACS Nano, 18(50), 34244-34256.
    

    

21. Hu, Jing-Jing, Jiang, Wenlian, Qiao, Yujuan, Ma, Qun, Du, Qiujiao, Jiang, Jian-Hui, Lou, Xiaoding(*), Xia, Fan. (2023). Enzyme Regulating the Wettability of the Outer Surface of Nanochannels. ACS Nano, 17(12), 11935-11945.
    

    

22. Wang, Haoran, Li, Qiyao, Alam, Parvej, Bai, Haotian, Bhalla, Vandana, Bryce, Martin R., Cao, Mingyue, Chen, Chao, Chen, Sijie, Chen, Xirui, Chen, Yuncong, Chen, Zhijun, Dang, Dongfeng, Ding, Dan, Ding, Siyang, Duo, Yanhong, Gao, Meng, He, Wei, He, Xuewen, Hong, Xuechuan, Hong, Yuning, Hu, Jing-Jing, Hu, Rong, Huang, Xiaolin, James, Tony D., Jiang, Xingyu, Konishi, Gen-ichi, Kwok, Ryan T. K., Lam, Jacky W. Y., Li, Chunbin, Li, Haidong, Li, Kai, Li, Nan, Li, Wei-Jian, Li, Ying, Liang, Xing-Jie, Liang, Yongye, Liu, Bin, Liu, Guozhen, Liu, Xingang, Lou, Xiaoding(*), Lou, Xin-Yue, Luo, Liang, McGonigal, Paul R., Mao, Zong-Wan, Niu, Guangle, Owyong, Tze Cin, Pucci, Andrea, Qian, Jun, Qin, Anjun, Qiu, Zijie, Rogach, Andrey L., Situ, Bo, Tanaka, Kazuo, Tang, Youhong, Wang, Bingnan, Wang, Dong, Wang, Jianguo, Wang, Wei, Wang, Wen-Xiong, Wang, Wen-Jin, Wang, Xinyuan, Wang, Yi-Feng, Wu, Shuizhu, Wu, Yifan, Xiong, Yonghua, Xu, Ruohan, Yan, Chenxu, Yan, Saisai, Yang, Hai-Bo, Yang, Lin-Lin, Yang, Mingwang, Yang, Ying-Wei, Yoon, Juyoung, Zang, Shuang-Quan, Zhang, Jiangjiang, Zhang, Pengfei, Zhang, Tianfu, Zhang, Xin, Zhang, Xin, Zhao, Na, Zhao, Zheng, Zheng, Jie, Zheng, Lei, Zheng, Zheng, Zhu, Ming-Qiang, Zhu, Wei-Hong, Zou, Hang, Tang, Ben Zhong. (2023). Aggregation-Induced Emission (AIE), Life and Health. ACS Nano, 17(15), 14347-14405.
    

    

23. Li, Shaoguang, Dai, Jun, Zhu, Man, Arroyo-Currás, Netzahualcóyotl, Li, Hongxing, Wang, Yuanyuan, Wang, Quan, Lou, Xiaoding(*), Kippin, Tod E., Wang, Shixuan, Plaxco, Kevin W., Li, Hui, Xia, Fan. (2023). Implantable Hydrogel-Protective DNA Aptamer-Based Sensor Supports Accurate, Continuous Electrochemical Analysis of Drugs at Multiple Sites in Living Rats. ACS Nano, 17(18), 18525-18538.
    

    

24. Yi, Xiaoqing, Hu, Jing-Jing, Dai, Jun, Lou, Xiaoding(*), Zhao, Zujin, Xia, Fan, Tang, Ben Zhong. (2021). Self-Guiding Polymeric Prodrug Micelles with Two Aggregation-Induced Emission Photosensitizers for Enhanced Chemo-Photodynamic Therapy. ACS Nano, 15(2), 3026-3037.
    

    

25. Dai, Jun, Li, Yinghao, Long, Zi, Jiang, Ruming, Zhuang, Zeyan, Wang, Zhiming, Zhao, Zujin, Lou, Xiaoding(*), Xia, Fan, Tang, Ben Zhong. (2020). Efficient Near-Infrared Photosensitizer with Aggregation-Induced Emission for Imaging-Guided Photodynamic Therapy in Multiple Xenograft Tumor Models. ACS Nano, 14(1), 854-866.
    

    

26. Dai, Jun, Cheng, Yong, Wu, Jun, Wang, Quan, Wang, Wenwen, Yang, Juliang, Zhao, Zujin, Lou, Xiaoding(*), Xia, Fan, Wang, Shixuan, Tang, Ben Zhong. (2020). Modular Peptide Probe for Pre/Intra/Postoperative Therapeutic to Reduce Recurrence in Ovarian Cancer. ACS Nano, 14(11), 14698-14714.
    

    

27. Yu, Peng, Wang, Fengmei, Shifa, Tofik Ahmed, Zhan, Xueying, Lou, Xiaoding(*), Xia, Fan, He, Jun. (2019). Earth abundant materials beyond transition metal dichalcogenides: A focus on electrocatalyzing hydrogen evolution reaction.Nano Energy, 58, 244-276.
    

    

28. Zhang, Wei, Yuan, Lizhen, Liu, Rui, Jing, Yanbo, Lin, Shijun, Fang, Hao, Li, Yuxuan, Zhang, Xiaohui, Dai, Jun, Liu, Tao, Xia, Fan, Lou, Xiaoding(*). (2025). A Covalent Self-Reporting Peptide Degrader Enables Real-Time Monitoring of Targeted Protein Degradation In Vivo. Journal of the American Chemical Society, 147(31), 27862-27875.
    

    

29. Yuan, Lizhen, Yang, Liang, Song, Wen, Song, Haoyang, Hu, Jing-Jing, Lou, Xiaoding(*), Xia, Fan, Yoon, Juyoung. (2025). Photochemical Generation of Peroxynitrite: Concurrent Inhibition of Glycolysis and Glutamine Metabolism for Enhanced Metabolic Therapy.Journal of the American Chemical Society, 147(36), 32610-32624.
    

    

30. Li, Yuxuan, Su, Yeyu, Wang, Haoyu, Xie, Yuanzhe, Wang, Xin, Chang, Liying, Jing, Yanbo, Zhang, Jiayi, Ma, Jun-An, Jin, Hongwei, Lou, Xiaoding(*), Peng, Qian, Liu, Tao. (2024). Computation-Guided Discovery of Diazole Monosubstituted Tetrazines as Optimal Bioorthogonal Tools.Journal of the American Chemical Society, 146(39), 26884-26896.
    

    

31. Wu, Jun, Wang, Quan, Dong, Xiaoqi, Xu, Min, Yang, Juliang, Yi, Xiaoqing, Chen, Biao, Dong, Xiyuan, Wang, Ying, Lou, Xiaoding(*), Xia, Fan, Wang, Shixuan, Dai, Jun. (2021). Biocompatible AIEgen/p-glycoprotein siRNA@reduction-sensitive paclitaxel polymeric prodrug nanoparticles for overcoming chemotherapy resistance in ovarian cancer.Theranostics, 11(8), 3710-3724.Dai, Jun, Xu, Min, Wang, Quan, Yang, Juliang, Zhang, Jinjin, Cui, Pengfei, Wang, Wenwen, Lou, Xiaoding(*), Xia, Fan, Wang, Shixuan. (2020). Cooperation therapy between anti-growth by photodynamic-AIEgens and anti-metastasis by small molecule inhibitors in ovarian cancer.Theranostics, 10(5), 2385-2398.
    

    

32. Dai, Jun, Xu, Min, Wang, Quan, Yang, Juliang, Zhang, Jinjin, Cui, Pengfei, Wang, Wenwen, Lou, Xiaoding(*), Xia, Fan, Wang, Shixuan. (2020). Cooperation therapy between anti-growth by photodynamic-AIEgens and anti-metastasis by small molecule inhibitors in ovarian cancer. Theranostics, 10(5), 2385-2398.
    

    

33. Long, Zi, Dai, Jun, Hu, Qinyu, Wang, Quan, Zhen, Shijie, Zhao, Zujin, Liu, Zitong, Hu, Jing-Jing, Lou, Xiaoding(*), Xia, Fan. (2020). Nanococktail Based on AIEgens and Semiconducting Polymers: A Single Laser Excited Image-Guided Dual Photothermal Therapy. Theranostics, 10(5), 2260-2272.
    

    

34. Hu, Jing-Jing, Jiang, Wenlian, Yuan, Lizhen, Duan, Chong, Yuan, Qiming, Long, Zi, Lou, Xiaoding(*), Xia, Fan. (2021). Recent advances in stimuli-responsive theranostic systems with aggregation-induced emission characteristics. Aggregate, 2(1), 48-65.
    

    

35. Zhang, Wei, Hu, Jing-Jing, Liu, Rui, Dai, Jun, Yuan, Lizhen, Liu, Yiheng, Chen, Bochao, Gong, Mingxing, Xia, Fan, Lou, Xiaoding(*). (2023). A Peptide-Conjugated Probe with Cleavage-Induced Morphological Change for Treatment on Tumor Cell Membrane. Advanced Science, 10(11), 2207228.
    

    

36. Dai, Jun, Dong, Xiaoqi, Liu, Rui, Chen, Biao, Dong, Xiyuan, Wang, Quan, Hu, Jing-Jing, Xia, Fan, Lou, Xiaoding(*). (2022). A peptide-AIEgen nanocomposite mediated whole cancer immunity cycle-cascade amplification for improved immunotherapy of tumor. Biomaterials, 285, 121528.
    

    

37. Li, Jianqing, Dai, Jun, Zhuang, Zeyan, Meng, Zijuan, Hu, Jing-Jing, Lou, Xiaoding(*), Xia, Fan, Zhao, Zujin, Tang, Ben Zhong. (2022). Combining PD-L1 blockade with immunogenic cell death induced by AIE photosensitizer to improve antitumor immunity. Biomaterials, 291, 121899.
    

    

38. Hu, Rong, Chen, Bin, Wang, Zhiming, Qin, Anjun, Zhao, Zujin, Lou, Xiaoding(*), Tang, Ben Zhong. (2019). Intriguing "chameleon" fluorescent bioprobes for the visualization of lipid droplet-lysosome interplay. Biomaterials, 203, 43-51.
    

    

39. Zhen, Shijie, Yi, Xiaoqing, Zhao, Zujin, Lou, Xiaoding(*), Xia, Fan, Tang, Ben Zhong. (2019). Drug delivery micelles with efficient near-infrared photosensitizer for combined image-guided photodynamic therapy and chemotherapy of drug-resistant cancer. Biomaterials, 218, 119330.
    

    

40. Zhan, Shenshan, Pan, Yong, Gao, Zhong Feng, Lou, Xiaoding(*), Xia, Fan. (2018). Biological and chemical sensing applications based on special wettable surfaces. TrAC Trends in Analytical Chemistry, 108, 183-194.
    

    

41. Chen, Yanxia, Min, Xuehong, Zhang, Xiqi, Zhang, Feilong, Lu, Simeng, Xu, Li-Ping, Lou, Xiaoding(*), Xia, Fan, Zhang, Xueji, Wang, Shutao. (2018). AIE-based superwettable microchips for evaporation and aggregation induced fluorescence enhancement biosensing. Biosensors and Bioelectronics, 111, 124-130.
    

    

42. Hu, Jing-Jing, Dong, Xiaoqi, Jiang, Wenlian, Xia, Fan, Lou, Xiaoding(*). (2021). Multifunctional aggregates for precise cellular analysis. Science China Chemistry, 64(11), 1938-1945.
    

    

43. Yao, Hongming, Dai, Jun, Zhuang, Zeyan, Yao, Jinya, Wu, Zixuan, Wang, Shixuan, Xia, Fan, Zhou, Jian, Lou, Xiaoding(*), Zhao, Zujin. (2020). Red AIE conjugated polyelectrolytes for long-term tracing and image-guided photodynamic therapy of tumors. Science China Chemistry, 63(12), 1815-1824.
    

    

44. Quan, Wang, Xudong, Wang, Min, Xu, Lou, Xiaoding(*), Fan, Xia. (2019). One-dimensional and two-dimensional nanomaterials for the detection of multiple biomolecules. Chinese Chemical Letters, 30(9), 1557-1564.
    

    

45. Yang, Juliang, Hu, Jing-Jing, Wei, Jiaming, Dai, Jun, Liu, Rui, Xia, Fan, Lou, Xiaoding(*). (2022). Peptide-Conjugated Aggregation-Induced Emission Fluorogen: Precise and Firm Cell Membrane Labeling by Multiple Weak Interactions. CCS Chemistry, 4(2), 464-475.
    

    

46. Hu, Jing-Jing, Lin, Niya, Jiang, Wenlian, Liu, Rui, Lou, Xiaoding(*), Xia, Fan. (2026). Functionalized two-dimensional nanochannel membranes to distinguish methylated/unmethylated peptides for sensing cellular G9a protein. Chemical Science, 17, 5648-5660.
    

    

47. Xu, Min, Wang, Xudong, Wang, Quan, Hu, Qinyu, Huang, Kaixun, Lou, Xiaoding(*), Xia, Fan. (2019). Analyte-responsive fluorescent probes with AIE characteristic based on the change of covalent bond. Science China Materials, 62(9), 1236-1250.
    

    

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