Gender:Female
Date of Employment:2025-03-01
吴霞
Click:
The Last Update Time:..
Degree:Doctoral Degree in Engineering
Education Level:Doctoral Degree in Education
Status:在岗
School/Department:Department of Chemistry
Honors and Titles:
优秀研究生
PostalAddress:
email:
吴霞，博士，预聘副教授，硕士生导师，主要围绕药物先导化合物的发现及生命复杂疾病的检测治疗等方面开展系列工作。在天然产物分离、抗肿瘤增值与迁移研究、荧光分子探针合成、高灵敏端粒酶检测及其循环放大检测的相关研究中已取得系列突破。实现了靶向抗癌活性物质的分离筛选，化学/生物分子在复杂体系（如细胞、组织切片）中高灵敏、高特异性的检测。相关工作以第一作者及共同第一作者发表SCI论文多篇，包括1篇Angewandte Chemie International Edition，1篇Analytical Chemistry，1篇Nano Letters，1篇National Science Review，1篇Advanced Optical Materials，1篇Acs Materials Letters，1篇Journal of Medicinal Chemistry及1篇Small等。其中1篇论文入选 ESI 1%高被引论文；H指数11。相关成果已获得国家授权发明专利1项，受理中国发明专利1项，参与及主持省部级项目多项。
科研论文：
1. Wu Xia , Zhang Hao , Li Mingxuan , Lou Xiaoding , Xia Fan , Dai Jun. Spatiotemporally traceable peptide self-Assemblies for mitochondrial-specific dysfunction. Anal. Chem.，2025 97 (34), 18584-18592.
2. Wu Xia , Zhang Hao , Li Mingxuan , Lou Xiaoding , Xia Fan. Recent progresses of peptide fluorescent probes for protein analysis in living cells. ACS Materials Letter, 2025, 7: 2524-2533.
3. Wu Xia, Hu Jing-Jing, Rui Liu, Chong Duan, Xia Fan, Lou Xiaoding. A Universal and Programmable Platform based on Fluorescent Peptide-Conjugated Probes for Detection of Proteins in Organelles of Living Cells. Angew. Chem. Int. Ed., 2024, 136(17): e202400766.
4. Wu Xia, Hu Jing-Jing, Chen Lulu, Chen Zhaojun, Wang Tingting, Wu Feng, Dai Jun, Xia Fan, Lou Xiaoding. Targeting proteins in nucleus through dual-regulatory pathways acting in cytoplasm. Nano Lett, 2023, 23, 12, 5811–5821.
5. Wu Xia, Hu Jing-Jing, Chen Lulu, Wu Feng, Xia Fan, Lou Xiaoding. Peptide modified AIEgen probe for selective imaging and killing drug-resistant cancer cells based on cell cycle dependent uptake. Adv. Opt. Mater., 2023, 2300850.
6. Wu Xia, Wu Jun , Dai Jun, Chen Biao, Chen Zhe, Wang Shixuan, Wu Feng, Lou Xiaoding*, Xia Fan. Aggregation-induced emission luminogens reveal cell cycle-dependent telomerase activity in cancer cells. Natl Sci Rev., 2021, 8(6): nwaa306.
7. Wu Xia, Guo yue, Dai Jun, Fan Xia, Lou Xiaoding*. A new technique for telomerase detection based on post-synchronous analysis, Chin Sci Bull, 2021, 66 (17): 2090-2092.
8. Dai Jun (#), Wu Xia (#), Ding Siyang (#), Lou Xiaoding*, Xia Fan, Wang Shixuan, Hong Yuning*, Aggregation-induced emission photosensitizers: from molecular design to photodynamic therapy, J. Med. Chem., 2020, 63, 1996-2012.
9. Wu Feng (#), Wu Xia (#), Duan Zhijuan, Huang Yu, Lou Xiaoding*, Xia Fan*. Biomacromolecule-functionalized AIEgens for advanced biomedical studies. Small. 2019 (32): e1804839.
10. Wu Xia, Fang Li-Zhen, Liu Feng-Lou, Pang Xue-Jiao, Qin Hai-Li, Zhao Ting, Xu Lu-Lin, Yang Deng-Feng, Yang Xiao-Long*. New prenylxanthones, polyketide hemiterpenoid pigments from the endophytic fungus Emericella sp XL029 and their anti-agricultural pathogenic fungal and antibacterial activities. RSC Advances, 2017, 7: 31115-31122.
11. Wu Xia, Pang Xue-Jiao, Xu Lu-Lin, Zhao Ting, Long Xin-Yu, Zhang Qiong-Yin, Qin Hai-Li, Yang Deng-Feng*, Yang Xiao-Long*. Two new alkylated furan derivatives with antifungal and antibacterial activities from the plant endophytic fungus Emericella sp. XL029. Nat. Prod. Res. 2017, 32(22):1-7.
科研项目经历
1、国家自然科学基金-青年科学基金项目（C类），项目起止年月：2026.01-2028.12，在研，主持。
2、广东省基础与应用基础研究区域联合基金-青年项目，项目起止年月：2023.11-2026.10，在研，主持。
3、湖北省自然科学基金-青年项目，项目起止年月：2024.03-2026.03，在研， 主持。
4、中国博士后科学基金-面上资助，项目起止年月：2023.12-2025.06, 结题，主持。
5、国家重点研发计划，“微纳米尺度调控的POCT生物传感器件在子宫内膜癌筛查中的应用研究”，2020.11~2025.12，在研，参与。
- 2011.9 -- 2015.6中国药科大学 , Master's Degree in Science , Editor
- 2015.9 -- 2018.6重庆大学 , Master's Degree in Science , The graduate student is educated
- 2018.9 -- 2022.6中国地质大学(武汉) , Doctoral Degree in Science , Doctoral Degree in Education
- 2022.7 -- Now中国地质大学(武汉) , 材料与化学学院 , 助理研究员 , 在职
- 2023.6 -- 2024.7Biomedical Engineering Communications杂志青年编委
No content
Copyright © China University of Geosciences, Wuhan